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Clinical Postdoctoral Researcher

  1. Date: 13.12.2017
  2. Location: Champalimaud Centre for the Unknown, Lisbon, Portugal
  3. Employer: Champalimaud Foundation
  4. Job type: Full Time
  5. Position: Translational Research
  6. Application start: 13.12.2017            

  7. Call for a Clinical Postdoctoral Researcher

    As part of the research activities, the ImmunoSurgery Lab is looking to initiate a translational project centred in developing and processing cellular products. The successful applicant is expected to be pivotal co-worker in the development and improvement of immune cell-based therapies for malignant diseases.

    Duties & Responsibilities
    o Lab management and organisation with an excellent team and collaborative spirit within the institution and with our international partners.
    o Close interaction with clinical colleagues and within immunotherapeutic programs.
    o Development of GMP structures for immunotherapeutic approaches including regulatory topics.
    o ‘Deep dive’ analysis and interpretation of immune responses
    o Procurement of cellular products for (non-vector and vector-based) therapy
    o Identification and development of new pre-clinical processes and candidate targets for the biological therapy of cancer

    Qualifications & Skills
    o Strong knowledge in human T-cell and B-cell biology and immunology, T- and B-cell propagation for immunological therapies with emphasis on ex-vivo T-cell expansion, T-cell based therapy and antigen-driven cellular immune responses.
    o Documented and well advanced practical and theoretical knowledge in (human) T-cell cloning, T-cell receptor, B-cell receptor structure / analysis and biology, DNA cloning and (vector, e.g. lentiviral) guided transfer of genetic material into recipient cells.
    o Very good knowledge in molecular technologies, recombinant protein expression, excellent knowledge in flow cytometry, T-cell sorting and gauging immune effector functions.
    o Exposure to clinical trial structures and SOP development within immunotherapy, dedication to enhance academic medicine within immunotherapy, strong interface with clinical partners.
    o Team spirit and will to collaborate within the foundation and with our partner institutions with the possibility to travel for clinical, international projects.
    o Fluency in Portuguese and excellent communication skills (written and verbal) in English.

    About Us
    Research is at the heart of the Champalimaud Centre for the Unknown, a modern research and clinical facility situated on the waterfront in Lisbon, Portugal. Champalimaud Research comprises a team of over 250 scientists from around the world with foci in neuroscience and cancer research. English is the official language of the Centre. Lisbon’s sunny Atlantic-Mediterranean climate, vibrant culture and high quality of life make this a great place to live and work.

    How to apply
    To apply, please send a letter of motivation, a 2-page CV and the names and contact information of 2 references to markus.maeurer@fundacaochampalimaud.pt with “Clinical Postdoc [your last name]” in the subject line.
    Position will remain open until filled.

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